Indiana's Historic Pathways
US 50 and US 150 across southern Indiana, from Vincennes on the Wabash to the Ohio River at Lawrenceburg, through hills, forests and old towns.
Also known as US 50 and US 150 across southern Indiana
Photo: U.S. Department of Transportation, America's Byways collection (National Archives), Public domain, source
- Length250 miles[1]
- Drive timeOne day[1]FHWA's "time to allow"
- RoadsUS 50/US 150 from the Illinois line east through Shoals, then US 50 northeast through Lawrenceburg to the Ohio line[2]
- Start and endThe Illinois line at Vincennes to the Ohio line near Lawrenceburg[2]
- Fees and passesNone[1]
- Best seasonNot verified
- SurfaceNot verified
- Vehicle notesNot verified
- Seasonal closuresNot verified
Before you go
Road status and weather can change quickly. Check the official road-conditions link before you go.
Facts last checked against the sources on October 22, 2026.
About the drive
Indiana's Historic Pathways crosses the southern part of the state on US 50 and US 150, a corridor FHWA says began as a bison trace and became a pioneer road and stagecoach route before the modern highways.
It starts at the Illinois line at Vincennes, where George Rogers Clark National Historical Park stands on the Wabash River, and runs east through rolling hills and forest to Shoals, then northeast on US 50 to Lawrenceburg on the Ohio River.
It's a full day's drive end to end, with historic town centers and countryside in between.
Stops along the way
-
George Rogers Clark National Historical Park
Memorial in Vincennes on the Wabash River.
Official information · 38.67781, -87.5355 · about 2.2 mi from the route line
-
Shoals
Small town where the route turns northeast onto US 50.
Official information · 38.66645, -86.79111 · about 0.0 mi from the route line
-
Lawrenceburg
River town near the Ohio line.
Official information · 39.0909, -84.84996 · about 0.5 mi from the route line
Stops are listed in order along the route; the numbers match the map. Stop locations come from the National Park Service, the U.S. Geological Survey place-names database, the stop's own official page or, where noted in the data, OpenStreetMap (© OpenStreetMap contributors).
Food along the way
Farmers markets within about 25 miles
- Bedford Farmers MarketBedford, IN · about 0.0 mi from the route
- Downtown Seymour Farmers' MarketSeymour, IN · about 0.1 mi from the route
- Floyds Knobs Farmers MarketFloyds Knobs, IN · about 0.1 mi from the route
- New Albany Farmers MarketNew Albany, IN · about 0.1 mi from the route · listed as year-round
- Dillsboro Farmers MarketDillsboro, IN · about 0.3 mi from the route
Markets keep their own seasons and hours, so check with the market before you go. Find more in the Farmers Market Finder.
Sources
- America's Byways: Indiana's Historic Pathways (FHWA) (checked 2026-10-22)
- Indiana Register, 105 IAC scenic byway definitions (Indiana Department of Transportation, July 2025) (checked 2026-10-22)
- George Rogers Clark National Historical Park (NPS) (checked 2026-10-22)
- Route line: U.S. DOT scenic byways map service (geo.dot.gov), retrieved 2026-10-22.
Written by VanillaGoods from the cited official sources. This is a drive to know, not a ranking. Road status and weather can change quickly; check the official road-conditions link before you go.
Spot something out of date? Email help@vanillagoods.com (help@vanillagoods.com).